What Is Phenylpiracetam?
Phenylpiracetam (Phenotropil, Carphedon) is a piracetam derivative with a phenyl group attached to the pyrrolidone ring. Developed in Russia in 1983 for cosmonauts, it is estimated to be 20 to 60 times more potent than piracetam by weight and has both cognitive-enhancing and psychostimulant properties. It is banned by WADA for competitive sport due to its stimulant effects.
How Phenylpiracetam Works
Phenylpiracetam retains piracetam’s AMPA receptor modulation and cholinergic enhancement while adding dopamine and norepinephrine reuptake inhibition from the phenyl group. This dual mechanism explains its stimulatory properties (increased alertness, motivation, physical endurance) alongside the cognitive benefits common to racetams. It also has cold tolerance properties, which is why it was developed for space missions.
Phenylpiracetam Dosage
Standard research dose: 100 to 300 mg per day, taken in 1 to 2 doses. Tolerance develops faster than with piracetam, so many researchers cycle it (e.g., weekdays on, weekends off). Half-life: 3 to 5 hours. Take in the morning to avoid insomnia.
Clinical Evidence
Clinical data is primarily from Russian studies. A 2010 study showed improved cognitive function and reduced depression/anxiety in post-stroke patients. A 2005 study found enhanced physical performance and cold tolerance. Western peer-reviewed data is limited. Phenylpiracetam gained international attention when Olympic biathlete Olga Pyleva tested positive for Carphedon in 2006 and was stripped of her medal, highlighting its performance-enhancing properties.
Phenylpiracetam vs Piracetam: How They Compare
Phenylpiracetam offers stronger stimulatory and physical performance effects than piracetam, but with important trade-offs: faster tolerance development (requires cycling), shorter half-life (more frequent dosing), WADA ban (unusable for competitive athletes), and a much smaller clinical evidence base. Piracetam is the better choice for long-term daily cognitive support without tolerance, with 50+ years of safety data. For researchers seeking the foundational, evidence-backed racetam, piracetam remains the standard.
Legal Status in Canada
Phenylpiracetam is not a controlled substance in Canada. It is banned by WADA for competitive sport. Available for research purposes.
Related Resources
- Piracetam Dosage Guide
- Piracetam Side Effects
- Buy Piracetam in Canada
- The Complete Guide to Racetam Nootropics
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Elite Bio Supply sells research compounds for research purposes only. This content does not constitute medical advice. The information above is based on published clinical literature and is provided for informational purposes. Consult a qualified physician before starting any protocol.