Quick Answer: Enclomiphene Citrate Dosage
The commonly referenced research dosage range for Enclomiphene Citrate is 6.25 to 25 mg per day. 12.5 mg daily (quarter tablet) Most clinical literature uses 50 mg tablets, 5-count as the standard form of administration.
Standard Research Dosage
Phase II and III trials by Repros Therapeutics used 12.5 mg and 25 mg daily doses. The 12.5 mg dose raised testosterone to the normal range in most subjects. The short half-life (10 hours) means enclomiphene does not accumulate like zuclomiphene in Clomid, reducing estrogenic side effects.
The dosage figures below are drawn from published clinical studies and manufacturer documentation. They are provided for informational purposes only and do not constitute prescribing guidance.
| Starting Dose | 12.5 mg daily (quarter tablet) |
|---|---|
| Maintenance Dose Range | 6.25 to 25 mg per day |
| Form | 50 mg tablets, 5-count |
| Dose Per Tablet | Quarter to half a tablet daily (50 mg tablets) |
| Timing | Taken once daily, morning preferred. Half-life of 10 hours means consistent daily dosing maintains stable levels. |
Timing and Administration
Taken once daily, morning preferred. Half-life of 10 hours means consistent daily dosing maintains stable levels. Consistency in timing is frequently cited in research protocols as a factor in maintaining stable plasma concentrations.
Most protocols recommend taking Enclomiphene at the same time each day. Whether morning or evening administration is selected, the key factor is regularity across the duration of the research protocol.
Dosage by Form
Enclomiphene Citrate is supplied in 50 mg tablets, 5-count form at Quarter to half a tablet daily (50 mg tablets) per unit. Based on the standard research dosage range of 6.25 to 25 mg per day, this translates to the following daily intake:
Researchers should calculate the number of tablets required based on the specific protocol dose and the per-tablet strength. For example, if the research dose is at the lower end of the range, fewer tablets are required. At higher doses, more tablets per day may be needed.
Research Protocol Considerations
Phase II and III trials by Repros Therapeutics used 12.5 mg and 25 mg daily doses. The 12.5 mg dose raised testosterone to the normal range in most subjects. The short half-life (10 hours) means enclomiphene does not accumulate like zuclomiphene in Clomid, reducing estrogenic side effects.
Key points from the clinical literature:
- Start at the lower end of the dosage range and assess response before escalating.
- Duration of research protocols varies. Review the relevant study timelines before setting a protocol length.
- Enclomiphene is the purified trans-isomer of clomiphene. It selectively blocks estrogen receptors in the hypothalamus without the estrogenic accumulation caused by zuclomiphene (the cis-isomer present in Clomid). This raises LH and FSH, stimulating endogenous testosterone production with fewer estrogenic side effects.
- Adjustment may be needed based on body weight, individual response, and concurrent compounds.
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Elite Bio Supply sells research compounds for research purposes only. This content does not constitute medical advice. Dosage information is sourced from published clinical literature and is provided for educational reference. Consult a qualified physician before use.