Elite Bio Supply ships pharmaceutical-grade enclomiphene citrate (50 mg tablets, 5-count) to all Canadian provinces and territories. Orders are processed within 1 business day and dispatched via Canada Post Expedited Parcel with a tracking number. Enclomiphene citrate is not a controlled substance in Canada. No prescription is required to purchase it as a research compound.
About Enclomiphene Citrate: What You Are Ordering
| Also Known As | Trans-clomiphene |
|---|---|
| Form | 50 mg tablets, 5-count |
| Class | SERM (pure trans-isomer) |
| Research Dose | 12.5 to 25 mg per day |
| Legal Status | Not a controlled substance in Canada |
Each pack contains 5 tablets at 50 mg of enclomiphene citrate per tablet. Enclomiphene citrate is the purified trans-isomer of clomiphene citrate, isolated from the racemic mixture that makes up standard Clomid. Unlike conventional clomiphene citrate, which contains roughly equal parts of the estrogenic zuclomiphene isomer and the anti-estrogenic enclomiphene isomer, this product contains only the trans-isomer. This makes enclomiphene citrate a cleaner pharmacological tool for researchers interested in selective estrogen receptor modulation without the estrogenic activity contributed by zuclomiphene. Elite Bio Supply sources enclomiphene citrate from a licensed pharmaceutical-grade manufacturer and tests every batch through independent third-party laboratory analysis.
Clinical Background
Enclomiphene citrate has emerged as a subject of significant clinical research interest over the past 15 years, driven in large part by its potential as an alternative to testosterone replacement therapy (TRT) for men with secondary hypogonadism. Secondary hypogonadism, also referred to as hypogonadotropic hypogonadism, is characterized by low testosterone levels caused not by testicular failure but by insufficient stimulation from the hypothalamic-pituitary axis. Because enclomiphene blocks estrogen receptors in the hypothalamus and pituitary, it removes the inhibitory feedback that estrogen exerts on GnRH, LH, and FSH secretion, thereby stimulating the body’s own testosterone production. This preserves testicular volume and spermatogenesis, in contrast to exogenous testosterone, which suppresses both.
Clinical trials conducted by Repros Therapeutics, which developed enclomiphene under the brand name Androxal, demonstrated that enclomiphene citrate at doses between 12.5 mg and 25 mg per day produced statistically significant increases in morning testosterone levels while simultaneously raising LH and FSH. These findings were published in peer-reviewed journals including the Journal of Clinical Endocrinology and Metabolism and Fertility and Sterility. The Phase II and Phase III data showed that enclomiphene normalized testosterone in a majority of subjects with secondary hypogonadism, with a favorable tolerability profile. The compound did not complete the FDA approval pathway for commercial reasons rather than safety concerns, and it remains an active area of clinical and research interest.
The separation of enclomiphene from zuclomiphene is considered scientifically significant because zuclomiphene has a long half-life and accumulates in tissue, contributing to the visual side effects occasionally associated with long-term clomiphene citrate use. Enclomiphene, as the pure trans-isomer, has a shorter half-life and does not carry the same accumulation profile. Research suggests this makes it better tolerated over extended administration compared to racemic clomiphene. For researchers designing protocols to study hypothalamic-pituitary-gonadal axis recovery or the effects of selective anti-estrogenic stimulation in men, enclomiphene citrate offers a more targeted tool than conventional Clomid.
Quality and Third-Party Testing
Enclomiphene citrate is chemically distinct from racemic clomiphene, and verifying isomeric purity requires more sophisticated analytical methods than standard purity testing. Elite Bio Supply uses independent, accredited laboratories equipped with chiral HPLC to confirm isomeric purity in addition to overall compound concentration. Our certificates of analysis specify both the total clomiphene content and the enclomiphene to zuclomiphene ratio, ensuring you are receiving a product that is genuinely enriched in the trans-isomer to pharmaceutical specification.
Every batch is also screened for heavy metals, microbial contamination, and residual solvents before it is listed for sale. Our enclomiphene citrate is manufactured at a GMP-certified facility using pharmaceutical-grade excipients. The COA for the current batch is downloadable from the product page. We do not blend isomers after the fact or use rebranded racemic clomiphene in our enclomiphene product. These distinctions matter in research contexts where isomeric purity directly affects the validity of outcomes. If you require additional documentation for a specific batch, contact our support team and we will provide it promptly.
Transparency is a non-negotiable standard at Elite Bio Supply. Every compound we carry is tested, documented, and traceable. We do not rely on manufacturer certificates alone. Our independent testing protocol is the same regardless of compound, batch size, or price point.
How to Order
- Visit the product page at /product/enclomiphene-citrate-50mg-5-tablets/ and click Add to Cart.
- Review your cart and proceed to checkout.
- Enter your Canadian shipping address. We ship to all 10 provinces and 3 territories.
- Select your payment method. We accept major credit cards, Interac e-Transfer, and cryptocurrency (Bitcoin, Ethereum, Monero). Cryptocurrency orders receive a 10% discount applied automatically at checkout.
- Complete your order. A confirmation email arrives immediately, followed by a Canada Post tracking number within 1 business day of dispatch.
- Track your order at canadapost.ca using the number provided. Most Canadian addresses receive delivery within 2 to 7 business days of the ship date.
Shipping Across Canada
We ship from our Canadian fulfillment centre via Canada Post Expedited Parcel. Orders received before 2:00 PM Eastern Time on business days are typically dispatched the same day. Weekend and after-hours orders are dispatched the following business day. All orders include a tracking number sent by email at the time of shipment.
| Province / Territory | Estimated Delivery |
|---|---|
| Ontario, Quebec | 2 to 4 business days |
| British Columbia, Alberta | 4 to 6 business days |
| Manitoba, Saskatchewan | 4 to 5 business days |
| Nova Scotia, New Brunswick, PEI | 4 to 6 business days |
| Newfoundland and Labrador | 5 to 7 business days |
| Northern Territories | 7 to 10 business days |
We deliver enclomiphene citrate to researchers across Canada. Find delivery information for your city:
- Enclomiphene in Toronto
- Enclomiphene in Vancouver
- Enclomiphene in Montreal
- Enclomiphene in Calgary
- Enclomiphene in Edmonton
- Enclomiphene in Ottawa
- Enclomiphene in Winnipeg
- Enclomiphene in Quebec City
- Enclomiphene in Hamilton
- Enclomiphene in Halifax
Legal Status in Canada
Enclomiphene citrate is not listed as a controlled substance under Canada’s Controlled Drugs and Substances Act. It is not on any CDSA schedule, and it is not currently approved as a prescription drug in Canada, which means it does not carry prescription-drug restrictions in the way that clomiphene citrate (approved for ovulation induction) does. This makes enclomiphene citrate one of the more straightforwardly accessible research compounds available to Canadian researchers.
Elite Bio Supply sells enclomiphene citrate as a research compound for investigational use. Customers are responsible for ensuring their use is consistent with applicable laws in their province or territory. We recommend reviewing the Health Canada Prescription Drug List and CDSA schedules for the most current regulatory status. If you have questions specific to your situation, consult a healthcare or legal professional familiar with Canadian pharmaceutical law.
Frequently Asked Questions
What makes enclomiphene different from Clomid?
Standard Clomid (clomiphene citrate) is a racemic mixture containing roughly 38% enclomiphene (trans-isomer) and 62% zuclomiphene (cis-isomer). Zuclomiphene acts as a weak estrogen agonist and has a very long half-life, accumulating in tissue over extended use. Enclomiphene, the trans-isomer, is the primary anti-estrogenic component and has a much shorter half-life. Enclomiphene citrate is the purified trans-isomer only, with the zuclomiphene removed. This means enclomiphene provides a cleaner anti-estrogenic signal at the hypothalamus and pituitary without the estrogenic activity or tissue accumulation associated with the cis-isomer. For researchers specifically studying HPG axis stimulation in men, this distinction has significant implications for protocol design and outcome interpretation.
Does enclomiphene require a prescription in Canada?
No. Enclomiphene citrate is not currently listed on Health Canada’s Prescription Drug List, and it is not a controlled substance under the CDSA. It can be purchased without a prescription as a research compound. This is distinct from racemic clomiphene citrate (Clomid), which is an approved prescription drug in Canada for female infertility. If you have therapeutic goals rather than research goals, we recommend working with a physician who is familiar with off-label hormonal therapies, as they can provide appropriate medical oversight and monitoring.
Is the 50 mg tablet meant for one dose or multiple doses?
The 50 mg tablet is a single tablet at 50 mg. The commonly studied research dose for enclomiphene in the published clinical literature is 12.5 mg to 25 mg per day. At that range, a single 50 mg tablet would represent 2 to 4 individual daily doses. Researchers typically use a pill splitter to divide tablets into the desired dose increment. Pill splitters are inexpensive and widely available at pharmacies across Canada. The 5-tablet pack contains a total of 250 mg of enclomiphene citrate. Some higher-dose protocols in the literature have used 25 mg daily, in which case a 5-count pack would represent a 10-day supply.
Related Guides
- Enclomiphene for Post-Cycle Therapy
- Enclomiphene for Secondary Hypogonadism
- Enclomiphene Dosage Guide
- Enclomiphene Side Effects
- SERMs for Men: Complete Guide
Elite Bio Supply sells research compounds for research purposes only. This content does not constitute medical advice. Enclomiphene citrate is not approved by Health Canada as a drug for the treatment, cure, or prevention of any disease or medical condition. Consult a qualified healthcare professional before using any research compound. The information provided on this page is for informational and educational purposes only and is not a substitute for professional medical guidance.